S

Author:

September 11, 2023

mbg Spirituality & Relationships Editor

By Sarah Regan

mbg Spirituality & Relationships Editor

Sarah Regan is a Spirituality & Relationships Editor, and a registered yoga instructor. She received her bachelor’s in broadcasting and mass communication from SUNY Oswego, and lives in Buffalo, New York.

Image by Viktor Solomin / Stocksy

September 11, 2023

A person’s risk for depression comes down to a number of factors, both genetic and lifestyle-related. But according to new research published in Nature Mental Health1, there are seven specific lifestyle factors that can help reduce depression risk—even if you’re genetically predisposed. Here’s what they found.

For this study, researchers wanted to dig into not only which lifestyle factors can help reduce depression risk, but why they may reduce depression risk.

To do so, they examined data from nearly 290,000 people (13,000 of which had depression) over nine years, looking at their lifestyle habits, genetics, brain structure, immune system, and metabolic data.

The data came from the UK Biobank, a large medical database which includes genetic, health, and lifestyle information on participants.

They also examined MRI brain scans from nearly 33,000 participants, as well as looked for blood markers that show immune or metabolic problems.

And not only did they identify the seven more important lifestyle factors for preventing depression, but they also discovered that those lifestyle factors had the biggest impact on immune and metabolic function, which subsequently impact depression risk.

1. Healthy sleep: Getting healthy sleep (which the study authors note is seven to nine hours a night) was the most important factor overall, reducing the risk of depression by 22%
2. Never smoking: Reduced depression risk by 20%
3. Frequent social connection: Reduced depression risk by 18%, and was most protective against recurrent depressive disorder
4. Regular physical activity: Reduced depression risk by 14%
5. Low-to-moderate sedentary behavior: Reduced depression risk by 13%
6. Moderate alcohol consumption: Reduced depression risk by 11%. (“Moderate” is defined2 by the Centers For Disease Control & Prevention as no more than one drink per day for women, and two per day for men)
7. Healthy diet: Reduced depression risk by 6%

And in case you’re wondering about the compounding effects of multiple healthy lifestyle factors, the research further showed that adhering to all of these factors can decrease your risk of depression up to 57%.

Even those participants who showed the lowest genetic risk for depression were only 25% less likely to develop it compared to those who were more genetically predisposed, suggesting lifestyle factors could be more important than DNA when it comes to depression.

As study co-author and professor of clinical neuropsychology, Barbara Sahakian Ph.D. explains in a news release, “Although our DNA—the genetic hand we’ve been dealt—can increase our risk of depression, we’ve shown that a healthy lifestyle is potentially more important.”